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Fig. 3B. —Three-dimensional (3D) volumetric analysis shows improved detection of malignant growth rate in non-small cell lung cancer. L/H = length/height, L/W = length/width, W/H = width/height. (Adapted and reprinted with permission from [75]) (Courtesy of Yankelevitz DF, New York, NY) Follow-up 3D volumetric reconstruction image of same nodule performed 130 days after A reveals interval increase in volume to 234 mm³. Interval growth of nodule was not apparent on serial axial high-resolution CT images (not shown).