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Fig. 5D. —Three-dimensional T1-weighted gradient-echo MR images (TR/TE, 50/5; flip angle 45°; isotropic; 150-mm voxels) of heart; chambers were perfused with gadolinium gelatin solution before scanning. (Reprinted with permission from [25]) Heart of transgenic mouse model (overexpression of myosin light chain) of dilated cardiomyopathy showing direct acquisition horizontal long-axis section (C) and postprocessed volumetric rendering of isolated atria and ventricles (D). Note attenuated ventricular walls and enlarged chamber volumes in cardiomyopathy model.