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Fig. 14. "Target" sign in 37-year-old woman with history of lupus erythematosus. Contrast-enhanced axial CT image at level of mid abdomen shows diffuse marked circumferential thickening of colon. Target appearance is present, with enhancement of mucosa (short white arrow) and outer enhancement of muscular layer and serosa (long white arrow) surrounding low-attenuation edematous submucosa. Small amount of ascites is present (arrowhead).