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Fig. 2C. —Percutaneous ethanol injection guided by CO₂-enhanced sonography in 64-year-old woman with Child's class C cirrhosis [9] and hepatocellular carcinoma with new lesion during follow-up period. CO₂-enhanced sonogram with direct injection of carbon dioxide into proper hepatic artery shows 30-mm area of positive enhancement (arrowheads) that was seen in A and B in anterior superior segment. Injection of 6.0 mL of iodized oil-ethanol mixture (1:2) was guided by CO₂-enhanced sonography.