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Fig. 4D. —Extensive tumor circumference around trachea is seen on MR images in 80-year-old woman with papillary thyroid carcinoma. Photomicrograph of surgically resected specimen shows scattered foci of tumor invasion (arrows) between collagenous fibers of adventitia (arrowheads) but no deep invasion is identified. C = thyroid cartilage, asterisk = foci of tumor cells. (H and E, x 10)