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Fig. 1A. Functional MR images (group composite) of regional brain activation during cold task. Red—yellow areas represent brain regions that were more active (p < 0.01) in cold task compared with baseline task. Blue—purple areas indicate brain regions that were more active (p < 0.01) in baseline task than in cold task. Arrow indicates only site in which anterior cingulate gyrus was active during cold task; z-axis slice location is 40.