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Fig. 2B. —Functional MR images (group composite) of regional brain activation during pain task. Red—yellow areas represent brain regions that were more active (p < 0.01) in pain task compared with cold task. Blue—purple areas indicate brain regions that were more active (p < 0.01) in cold task compared with pain task. Pain-related activation is seen in anterior cingulate gyrus (straight arrow), in superior frontal gyrus bilaterally (arrowheads), and in right cuneus (curved arrow); z-axis slice location is 32.