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Fig. 2D. —Gross and histopathologic findings of excised fatty posterior mediastinal mass in 35-year-old woman. Photomicrographs of histologic specimens with immunohistochemical staining show positivity of spindle cells for smooth-muscle markers (arrows), confirming muscle differentiation. These findings are diagnostic of posterior mediastinal angiomyolipoma. (HHF-35 stain, [muscle common actin] x40 [C] and HMB-45, [human melanoma, black-45] x40 [D])