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Fig. 12B. 43-year-old woman with history of extensive travel to numerous developing countries evaluated for suspected lymphedema. Results of multiple examinations for infection—including filarial disease—were negative. Lymphoscintigram of lower extremities shows dermal backflow (arrow) in right calf, with otherwise prompt lymphatic drainage in both legs. No right lymphocele or other right thigh lymphatic abnormality is revealed. Left leg is unremarkable. Findings are consistent with obesity ("lipedema") with relatively minor lymphatic abnormality in right calf unrelated to obesity.