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Fig. 8. —Graph shows comparison of average receiver operating characteristic (ROC) curves for all observers without and with artificial neural network (ANN) output and ROC curves for ANN output alone. Note that observer performance with ANN output was significantly higher than that without ANN or than that with ANN alone. Solid line = with ANN (A_z = 0.959), dotted line = ANN alone (A_z = 0.951), dashed line = without ANN (A_z = 0.831).