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Fig. 1A. —Assessment of fractional lung function by quantitative CT versus perfusion scintigraphy. Preoperative forced expiratory volume in 1 sec (FEV₁) in 73-year-old man with chronic dyspnea with recent hemoptysis for 2 months was 1.21 L. FEV₁ after left-sided pneumonectomy was 0.81 L. Loss of FEV₁ was 33%, close to prediction by quantitative CT. Quantitative CT map shows "functional lung volume" of representative slice. Lung parenchyma was first outlined from mediastinum and chest wall by default range of -200 and -1,024 H (white-line contours). Tumor (Tu) was also excluded. After applying dual threshold, three segments in lung parenchyma were generated. White area below -910 H denoted emphysema (E), black area above -500 H denoted infiltration and atelectasis (I), and gray area between -500 and -910 H denoted functional lung volume (FLV). HT = heart.