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Fig. 2C. —64-year-old woman with cancer of unknown primary source and suspicious MR imaging—detected lesion of left breast. MR imaging—guided 14-gauge large-core needle biopsy with contrast-enhanced T1-weighted three-dimensional fast low-angle shot sequence was performed. Subtraction image obtained of unenhanced image from second contrast-enhanced T1-weighted MR image shows clearly enhancing breast lesion.