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Fig. 2A. —Six male control volunteers between 27 and 45 years old. Plots of T1 against time in Achilles tendon show decrease in T1 over 40 min-1.5 hr followed by return to normal values over 1-22 hr. Large error bars seen in these measurements reflect tissue heterogeneity in region of interest rather than intrinsic uncertainty in T1, which is shown by clear trends seen in data.