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Fig. 8. —^99mTc sestamibi-¹²³I subtraction scintigram in 45-year-old woman with hyperparathyroidism. Planar image obtained after subtraction of ¹²³I portion of study reveals focus of increased tracer uptake (large arrow) along inferior aspect of left lower portion of photopenic area, representing subtracted thyroid gland activity, consistent with parathyroid adenoma. Tracer uptake at superior aspect of image (small arrows) represents salivary tissue. (Courtesy of Newberg A, Philadelphia, PA)