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Fig. 5. —13-year-old boy with history of osteogenic sarcoma of right femur, shown after chemotherapy and radiation therapy and resection of right femoral osteosarcoma with placement of total-knee arthroplasty. MR images and CT scans (not shown) were deemed inadequate for tumor evaluation because of extensive metallic artifacts. Sagittal FDG positron emission tomography image shows no increased FDG uptake in area of right femur and knee. Cold defect (arrow) in region of right knee arthroplasty is visible.