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Fig. 3D. —15-year-old girl with rhabdomyosarcoma of right thenar eminence, shown after chemotherapy and radiation therapy. Coronal (C), axial (D), and sagittal (E) positron emission tomography images show focus of increased uptake (standardized uptake value, 6.5) in upper outer quadrant of left breast (arrow, C and D) and area of increased uptake (standardized uptake value, 4.3) in soft tissue overlying medial distal right humerus (arrow, E) that were suspicious for metastases. Subsequent biopsy of these two lesions revealed metastatic disease.