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Fig. 5B. —74-year-old woman with lung cancer. CT scan shows enhancement of spleen, renal cortex, and aorta after injection of 100 mL of contrast material and 50 mL of saline chaser with injection parameters identical to those used for A. Spleen (140.5 H), renal cortex (170.6 H), and aorta (187.8 H) are all slightly less enhanced compared with A. Decreased enhancement obtained with 100 mL of contrast material and chaser is generally not clinically important in patients with cancer, because metastases to spleen and kidney are relatively rare compared with hepatic metastases.