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Fig. 1. —Diagram of transverse CT scan of lesion shows method described by Schwartz [16] for calculating volume doubling time (VDT): VDT = t log 2 / (3 log Dt / D0), where t is interval between two CT scans, D0 is mean diameter at initial CT ([A + B] / 2), Dt is mean diameter at second CT, A is maximum transverse diameter of lesion, and B is perpendicular transverse diameter of lesion (b1 + b2).