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Fig. 3D. —52-year-old man with colorectal carcinoma who was treated with chemotherapy for liver lesions. Pulse inversion harmonic digital sonogram is second scan obtained at 100 sec after Levovist injection. In same area as in C, hypoechoic lesion (arrow) is now visible. Vessel simulating hyperechoic lesion with hypoechoic rim is visible (arrowhead); this appearance can mimic focal lesion when there is not careful comparison between unenhanced and contrastenhanced images.