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Fig. 1B. —60-year-old man with colorectal carcinoma and metastatic liver involvement suspected on sonography. Pulse inversion harmonic digital sonogram shows first scan obtained 20 sec after Levovist ([SH U 508A] Schering, Berlin, Germany) injection. Twenty seconds after Levovist administration, increased conspicuity of lesion (arrow) related to increased echogenicity of surrounding and still heterogeneous liver parenchyma is seen.