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Fig. 2E. Asymptomatic 57-year-old woman. Sonogram shows 0.7-cm hypoechoic solid mass in right breast at 12:30-o'clock position 3 cm from nipple (arrows) in region of density seen on screening mammogram. Analysis of sonographically guided 14-gauge automated large core biopsy specimen revealed infiltrating ductal carcinoma. At mastectomy, 4.0-cm infiltrating ductal carcinoma was found. In addition, axillary nodes were found to be positive for metastatic disease.