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Fig. 9B. —Results of CT measurements and calculations with three-compartment model for contrast medium concentrations in vascular space and interstitium in 74-year-old patient with good renal function treated with right-sided percutaneous nephrostomy for ureteral stone. Volume of both kidneys was 578 mL. Glomerular filtration rate (GFR) measured by plasma clearance was 113 mL/min. CT GFR was 129 mL/min. Lower curve (A and B) represents contrast medium concentration in interstitial space. Parameters are more fully defined in Appendix 1. Graph shows amount of contrast medium in vascular space, B(t) (); in interstitial space, I(t) (); and excreted into nephron based on model calculations and CT measurements. • = amount of contrast medium in nephron, N(t); = amount of contrast medium in kidney, K(t); = contrast medium measured with CT (K_CT).