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Fig. 10A. —Contrast medium concentrations as results of three-compartment model calculations and CT measurements in patient with markedly swollen kidneys (shown in Figs. 8A, 8B) caused by bilateral pyelonephritis with hydronephrosis and treated with percutaneous nephrostomy on left side. Patient had low glomerular filtration rate (GFR). Interstitial space was calculated to be 46%. Parameters are more fully defined in Appendix 1. Graph shows that contrast medium concentrations in vascular space as measured with CT, b(t) (), and in interstitium as calculated by formula in Appendix 1, I(t) (), are similar to those in patient with small interstitial space. = b(t) interpolated.