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Fig. 11. —Graph shows Patlak plot [3] of correlation between interstitial volume as calculated by three-compartment model and discrepancy of total glomerular filtration rate (GFR) as measured with CT and plasma clearance (n = 17 kidneys; coefficient correlation of r = 0.93). Each point represents data from total GFR of one patient; interstitial space represents sum of left and right kidneys. High correlation is found between interstitial space and overestimation of GFR as measured with CT.