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Fig. 4B. —75-year-old woman with inflammatory carcinoma of right breast and persistent segmentally distributed abnormalities on MRI after chemotherapy. Contrast-enhanced T1-weighted image after chemotherapy reveals persistent multifocal, segmentally distributed enhancement, which measured 6.1 cm in maximum extent. Skin thickening and enhancement in periareolar region are also evident. Histology review of breast after mastectomy showed 4.0-cm gross tumor with invasive and in situ ductal carcinoma. However, no multifocal tumor was shown outside this mass, and both nipple and skin were negative for malignancy. Nonneoplastic tissue did contain intraductal papilloma and fibrocystic changes.