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Fig. 1A. —Patterns of time–intensity curve and related parameters. Scanning began 5 sec after initiation of contrast injection. First breathing interval was 23–33 sec. Second breathing interval was 51–61 sec. Baseline signal intensity (SI) value (SIbase) in time–intensity curve = mean SI value on first three MR images obtained, SI1st = peak SI value in first-pass study of contrast enhancement, SImax= maximal SI value. Contrast rise time ({Delta}T in seconds) = time interval between SIbase and SI1st. In A (pattern 1) and C (pattern 3), SI1st = SImax. Pattern I is rapid wash-in phase followed by washout phase in latter portion.