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Fig. 3C. —In 57-year-old woman, multifocal tumor is seen on three successive slices (shown across each row) from lateral to medial parts of breasts. Initial MR images (A), MR images after two courses of chemotherapy (B), and preoperative MR images after completion of chemotherapy (C) all show two main central tumor nodules associated with smaller peripheral nodules (arrows, A) confined in one quadrant. B and C show nodule shrinkage in response to therapy but persistence of two small nodules on preoperative MR images (C). Patient is not suitable candidate for breast-conserving surgery.