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Fig. 3. —Phase-shift image taken 22.2 sec after onset of sonication in 38-year-old woman with symptomatic fibroids. High-signal area is visible due to rise in temperature and can be seen along sonication pathway. Signal is greatest within target spot and it is this area that has been heated sufficiently to cause irreversible damage. Heating of anterior pathway will be dissipated by perfusion during cooling period between sonications. Figure is screen capture from ExAblate 2000 system (InSightec) during treatment.