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Fig. 3B. —Coronal T1-weighted spin-echo MR images obtained with volume segmentation for intraabdominal adipose tissue. Contiguous images of 30-week-old lysosomal acid lipase–deficient mouse show red regions of interest that denote area of intraabdominal adipose tissue. Retroperitoneal and reproductive adipose tissue is less than that in control mouse, and fat deposition in bowel wall (arrows) is greater than that in control mouse. Hepatomegaly is present also.