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Fig. 11B. —33-year-old woman with acute lupus pneumonitis in systemic lupus erythematosus. 4-MDCT images show widespread centrilobular (arrowheads, B) and diffuse ground-glass opacity, confluent lower lobe air-space consolidation, and minimal pleural effusion. Appearances are nonspecific; diagnosis in patients without clinical diffuse alveolar hemorrhage is by lung biopsy or by exclusion.