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Fig. 4B. —77-year-old woman with chronic type C viral hepatitis and moderately differentiated 6.8-cm hepatocellular carcinoma showing moderate vascular endothelial growth factor (VEGF) expression, isointensity on in-phase T1-weighted, homogeneous moderate hyperintensity on T2-weighted, and heterogeneous, moderate enhancement on hepatic arterial dominant phase images. Child-Pugh grade was A. In-phase T1-weighted spoiled gradient-recalled echo (GRE) (TR/TE, 150/4.2) axial image shows hepatocellular carcinoma as virtually isointense lesion (arrow) without internal heterogeneity. Opposed-phase T1-weighted spoiled GRE (150/1.6) axial image (not shown here) shows hepatocellular carcinoma as homogeneous, moderately hypointense lesion. Signal intensity reduction was seen between in-phase and opposed-phase GRE images, indicative of presence of intratumoral fat deposition.