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Fig. 3A. —57-year-old man with chronic type C viral hepatitis and poorly differentiated 5.8-cm hepatocellular carcinoma showing high vascular endothelial growth factor (VEGF) expression, discrete hypointensity on in-phase T1-weighted, heterogeneous discrete hyperintensity on T2-weighted, and weak enhancement on hepatic arterial dominant phase images. Child-Pugh grade was A. Schematic shows electrophoretic bands and corresponding histograms in this patient. VEGF solution (1.25 mg/mL) was used for calibration. Area of histogram was 376 pixels for calibration band, 3,485 pixels for hepatocellular carcinoma band (HCC), and 1,395 pixels for surrounding liver band. VEGF expression index (VEGF^IND) was 9.27 in hepatocellular carcinoma and 3.71 in surrounding liver, giving VEGF^IND difference of 5.56. Note that electrophoretic peaks adjacent to those of hepatocellular carcinoma and liver are caused by expression of irregular protein.