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Fig. 3B. —57-year-old man with chronic type C viral hepatitis and poorly differentiated 5.8-cm hepatocellular carcinoma showing high vascular endothelial growth factor (VEGF) expression, discrete hypointensity on in-phase T1-weighted, heterogeneous discrete hyperintensity on T2-weighted, and weak enhancement on hepatic arterial dominant phase images. Child-Pugh grade was A. In-phase T1-weighted spoiled gradient-recalled echo (GRE) (TR/TE, 150/4.2) axial image shows hepatocellular carcinoma (arrow) as discrete hypointense lesion with internal areas of lower signal intensity (arrowhead). Likewise, opposed-phase T1-weighted spoiled GRE (150/1.6) axial image (not shown here) shows hepatocellular carcinoma as discrete hypointense lesion with internal areas of lower signal intensity.