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Fig. 5D. —Images of kidneys treated with hypertonic-saline (HS)-augmented bipolar (A–D) and (E and F) monopolar radiofrequency for 10 min in dog model. Nonenhanced areas were determined in each slice and summed to determine volume. Photomicrograph of radiofrequency ablation zone in kidney seen in A obtained 3 days after procedure shows confined area of coagulation necrosis (N) surrounded by peripheral zones of hemorrhage (H), and normal renal parenchyma (R). Note typical coagulation necrosis with preserved architecture of kidney having ghostlike tubular profiles with very faintly staining nuclei. (H and E, x40)