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Fig. 1A. —77-year-old man with bilateral internal carotid artery stenoses and compromised cerebral vasoreactivity. Measurement of cerebral vasoreactivity on color velocity imaging quantification. Before administration of acetazolamide (A), baseline blood flow volume of right common carotid artery was 379.0 mL/min. After acetazolamide administration (B), respective flow value decreased to 300.0 mL/min, decrease of approximately 21%.