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Fig. 5. Hepatic abscess mimicking malignant tumor in 57-year-old man with chronic hepatitis B. Native B-mode gray-scale sonogram (upper left) depicts heterogeneous low-echoic mass (arrow), which was interpreted as malignant tumor by both radiologists. On color Doppler sonogram (upper middle), faint vascularity (arrow) is noted at periphery of lesion. Serial contrast-enhanced agent detection images obtained 26 sec (upper right), 34 sec (lower left), 95 sec (lower middle), and 3 min (lower right) after injection show early heterogeneous enhancement of lesion (arrows) on arterial phases (upper right, lower left) and washout in portal (lower middle) and delayed (lower right) phases. On basis of these contrast-enhanced sonographic features, this lesion was incorrectly characterized as hepatocellular carcinoma and further imaging workup was not requested by either radiologist. Percutaneous sonographically guided aspiration and subsequent culture confirmed hepatic abscess infected by Klebsiella organisms.