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Fig. 3D. —63-year-old woman with osteoblastic bone metastases. Axial CT image (A), 3D maximum-intensity-projection CT image (B), sagittal SPECT image (C), and sagittal FDG PET image (D) show osteoblastic deposits in vertebral bodies have increase in uptake of ^99mTc hydroxymethylenediphosphonate (arrows) but not in uptake of FDG PET. Hypermetabolic lesion in mediastinum (arrowhead) was confirmed to be lymph node recurrence.