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Fig. 3B. —Two opposing examples of benign nodal disease appearance on PET/CT. In 19-year-old woman who presented with large right popliteal fossa mass, mass was proven by biopsy to be embryonal rhabdomyosarcoma. Axial CT (A), PET (B), and fused PET/CT (C) images show absence of FDG activity within enlarged retroperitoneal node (arrows). This node underwent biopsy and was found to be negative for tumor.