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Fig. 5B. —Graphs show calculated normalized signal intensity variation due to measured T1 and T2 versus gadolinium concentration for T1-weighted spin-echo sequence. Calculated graph for more heavily T1-weighted spin-echo sequence with TR/TE of 500/8. Note that for gadodiamide concentrations below about 1 mmol/L, the addition of iodinated contrast material should increase signal-to-noise ratio (SNR) for this sequence, although peak SNR achievable with iodinated contrast material is still less than that achievable with gadodiamide alone.