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Fig. 1F MR images of typical patient with Merkel cell carcinoma show one unique imaging finding of Merkel cell carcinoma: positive anatomic alignment of subcutaneous lymphatic tumor nodules. Patient is 63-year-old man with primary tumor in skin of right popliteal fossa. Enlargement of photomicrograph shown in E reveals subcutaneous tumor mass is composed of dense small blue cells with hyperchromatic nuclei, minimal cytoplasm, and frequent mitoses. These histologic features may account for slight increased signal intensity on T1 weighting within small subcutaneous nodules. (H and E, x10)