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Fig. 6 —Scatterplot of volumes of enhancing tumors determined on T1-weighted gadolinium versus T1-weighted ultrasmall superparamagnetic iron oxides (USPIO) images (icon triangle) and T1-weighted gadolinium versus T2^*-weighted USPIO images (icon diamond) with line of isovolume shown. In three cases, tumor volumes determined on basis of T1-weighted gadolinium, T1-weighted USPIO, and T2^*-weighted USPIO images were comparable. In one case, tumor volume was largest on T2^*-weighted USPIO, second largest on T1-weighted gadolinium, and smallest on T1-weighted USPIO. In one case, tumor volumes were comparable on T1-weighted gadolinium and T1-weighted USPIO, whereas tumor volume appeared to be much larger on T2^*-weighted USPIO. In two cases, tumor volumes were comparable in USPIO series, whereas they differed in size on T1-weighted gadolinium images. These differences were not statistically significant (p > 0.2).