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Fig. 2A —52-year-old man with lipofibromatous hamartoma of median nerve and macrodystrophia lipomatosa. Photograph of volar aspect of right hand and forearm shows local gigantism of thumb and radial half of index finger (arrowheads), with associated peripheral cyanosis. Scar (arrow) extending from thenar eminence proximally into forearm bears witness to previous surgical exploration and decompression of "fatty mass."