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Figure 4


Fig. 2B —Risk-to-benefit histograms for men and women stratified by age. Risk-to-benefit ratio (log units) histograms for males (A) and females (B) commencing 4 years of annual screening rounds on an MDCT (MD) or single-detector (SD) (low-dose thick-collimation plus one full-dose thin-collimation package) scanner in different age categories: 55-59, 60-64, and 65-69 years. Efficacy of screening is assumed to be 20% in reducing mortality in 8 years after start of program. For current smokers, risk-benefit ratio ranges between 0.21 in women who are 55-59 years old examined on a single-detector scanner and 0.008 in men who are 65-69 years old examined on an MDCT scanner.