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Fig. 1A —66-year-old woman with hypoattenuating lesion that progressed to hyper-in-hypoattenuating type (nodule-in-nodule hepatocellular carcinoma [HCC]) (group B1) and advanced to complete hyperattenuation (overt HCC) (group B2). Arterial phase CT scan shows 1.0-cm hypoattenuating lesion (arrow) in segment II of liver.