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Fig. 5B —71-year-old man with radiofrequency-treated hepatocellular carcinoma in unenhanced sonography group. After ablation, tumor was enlarged with suspected recurrence. Serum -fetoprotein value was 0.815 ng/mL. Initial biopsy guided by conventional sonography was negative. Contrast-enhanced sonograms obtained after ablation during arterial phase (A) and parenchymal phase (B) show 3.3 x 2.4 cm abnormal enhancement in lesion (arrow). Area of enhancement (arrow, A) in arterial phase washed out quickly in parenchymal phase (arrow, B). However, postablation lesion was not enhanced and presented as hypoechoic during all phases (arrowhead). Area of enhancement was punctured again, and well-differentiated hepatocellular carcinoma was diagnosed.