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Fig. 1C —T1-weighted dynamic contrast-enhanced relative permeability and T2^*-weighted dynamic susceptibility contrast (DSC) imaging studies in 51-year-old man with biopsy-proven glioblastoma multiforme. DSC spin-echo echo-planar image at trough signal period (maximal susceptibility effect) during bolus injection of contrast material obtained at same level as A shows decreased signal intensity within lesion in left temporal lobe compared with remainder of brain. Bright signal due to vasogenic edema is seen posterior to temporal lobe mass lesion.