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Fig. 1D —49-year-old woman underwent bilateral screening mammography. Patient presented with palpable mass 5 months after screening mammography. Stage II invasive ductal carcinoma was seen at biopsy. Right craniocaudal view 4 months later. Asymmetry was not marked by radiologist but was marked by computer-aided detection (CAD) on screening mammogram craniocaudal view. Mass (arrow) was not marked by CAD when patient returned with palpable mass. Linear markers on images are routinely placed on skin over visible incision sites in women who have previously undergone surgery.