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Fig. 5C —Direct imaging of angiogenesis in mouse model of
atherosclerosis using MRI and paramagnetic nanoparticles targeted against
ß3 integrin. (Reprinted with permission
from Winter PM, Morawski AM, Caruthers SD, et al. Molecular imaging of
angiogenesis in early-stage atherosclerosis with
ß3-integrin-targeted nanoparticles.
Circulation 2003; 108:2270-2274
[51].) Color-coded signal
enhancement image of B in which regions of greatest enhancement are
seen in yellow indicates that some portions of aortic wall have regions of
greater enhancement (and greater angiogenesis).