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Fig. 5B —72-year-old woman (patient 40 in Table 1) with rectal cancer recurrence. CT (A), PET (B), and fusion (C) images. Presacral lesion (arrow, A) was missed using CT alone and was interpreted as physiologic uptake by bowel (arrow, B) on PET alone and on side-by-side review of PET and CT images. Accurate diagnosis of local recurrence was obtained after interpretation of fused images.