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Figure 3


Fig. 1C 75-year-old man with prostate cancer. Hydrogen-1 MR spectroscopy from a voxel of nonmalignant peripheral zone on right (signal-to-noise ratio [SNR] = 4) (C) is compared with a spectrum from malignant peripheral zone nodule on left (SNR = 3) (D). Gray line shows data and black line represents fit using LCModel (Stephen Provencher, Inc.) (both smoothed for display using 5-point weighted average). Increase in choline (Cho) (3.2 ppm) and decrease in citrate (Cit) (2.6 ppm) are seen in D compared with C. In C, Cho/Cit ratio is 0.31; in D, 0.45. AU = arbitrary units.